根因医学 / Re-invent Medicine
Root Cause Medicine
A three-layer computational framework — phenotype layer, functional layer, and root cause layer
Full Definition
A medical paradigm centered on root cause analysis, not satisfied with symptom-level diagnosis but tracing disease origins to the functional layer and root cause layer. The three-layer computational framework: the phenotype layer corresponds to 'external manifestations after capability reserve depletion,' the functional layer corresponds to 'the intermediate process of capability reserve decline,' and the root cause layer corresponds to 'the underlying mechanisms causing capability reserve depletion.'
Deduction from First Principles
Deduced from the first principle:
1. If life is a capability ensemble, then disease is merely the external manifestation of capability reserve depletion (phenotype layer).
2. Why do capability reserves decline? The operational status of the functional layer must be analyzed (metabolic adaptation, immune adaptation, etc.).
3. Why is the functional layer abnormal? The root cause layer must be traced — genetic and epigenetic information.
4. Therefore, a complete medical analysis must encompass three layers: phenotype → function → root cause.
Why It Matters
Current medicine primarily diagnoses and treats at the phenotype layer, lacking a systematic root cause tracing framework. Root cause medicine provides a complete analytical pathway from symptoms to underlying causes.