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The same inflammation concept, measured via serum protein, shows weak correlation with brain health. Switch to a DNA methylation surrogate, and the correlation jumps 6.4x. The concept didn't change — the 'shutter speed' did. This is precisely the core insight behind EvoSika's methodology.

The mission of AI4S should not be using AI to accelerate existing science, but using AI to reinvent how science organizes knowledge. The content of a concept depends on the context of inquiry — we need an operating system for concepts.