生命第一性原理
First Principle of Life
Life is an adaptive capability ensemble
Full Definition
Life is an adaptive capability ensemble. From this axiom, unified definitions of health, aging, and disease can be deduced: health = robust adaptive capabilities with coordinated subsystems; disease = impaired or dysregulated adaptive capabilities; aging = the progressive decline of overall adaptive capabilities over time.
Deduction from First Principles
First principle: Life is an adaptive capability ensemble.
Deduction:
1. If life is a capability ensemble, then understanding life states requires characterizing capabilities.
2. Capabilities cannot be reduced to a single metric but constitute a set of measurable, comparable dimensions.
3. Therefore, a new conceptual system — capomics — must be established to describe the types, reserves, dynamic changes, and interactions of capabilities.
Why It Matters
Traditional biology lacks a unified foundational principle akin to physics, leading to fragmented medical knowledge and concepts. The first principle provides a logical starting point for reconstructing medicine.